Myth: It’s just heartburn.

Fact: Chronic heartburn and GERD can lead to esophageal cancer—even if you’re effectively controlling your symptoms with medication.

EsoGuard accurately detects precancerous cells in the 
esophagus1, 2, 3 early, so you can take action before they turn
into something more serious.

Fact: Chronic heartburn and GERD can lead to esophageal cancer—even if you’re effectively controlling your symptoms with medication.
EsoGuard accurately detects precancerous cells in the esophagus1, 2, 3 early, so you can take action before they turn into something more serious.
Adult male showing signs of chest pain or burning sensation, commonly associated with heartburn or GERD symptoms.

We accept most insurance plans

Fact: Esophageal cancer is the #1 increasing cancer diagnosis and the #2 deadliest form of cancer in the U.S. 4

Esophageal Adenocarcinoma (EAC) has increased over 500% in the past 4 decades. 5, 6
Older man jogging outdoors with a friend, smiling and wearing sportswear.

Fact: The disease that leads to esophageal cancer is treatable

EsoGuard has unprecedented detection rates for precancer, so you can take action before cells become cancerous.

Developed through the National Cancer Institute

See if EsoGuard is right for you

How it works

Older man sitting on a couch and smiling while using a tablet.
Complete our medical questionnaire
Create your account and fill out a brief intake survey.
Man attending an online medical consultation with a senior doctor via video call on a laptop.
Meet virtually with a physician
During your telehealth visit, your provider will determine if EsoGuard is right for you and order the test if indicated.
Doctor consulting with an older male patient during a medical appointment.
Get tested
You will be contacted to schedule an in-person office visit where a clinician will administer the test. Results will be available within 3 weeks.

Risk Factors

Some patients are at increased risk for developing esophageal precancer and cancer. If you meet 3 or more of the below criteria, you should get tested:
  • Chronic heartburn or GERD
  • Male
  • 50+ years old
  • Obesity
  • White
  • History of tobacco smoking
  • Family history of Barrett’s Esophagus or Esophageal Cancer
Bald man with glasses enjoying a cup of coffee while sitting near a window.

Frequently Asked Questions

Where can I get the EsoGuard test?
If your physician determines EsoGuard is right for you during your telehealth consultation, they will prescribe an in-office visit for the test. The test takes less than 5 minutes to complete.
How soon will I get my results back?
Your test results will be available within a few weeks.
How much does the EsoGuard test cost? 
We accept most forms of insurance. Please contact our care team at (877) 202-8469 for more information.

Take control of your health with EsoGuard

References:
1. Moinova, Helen R et al. “Multicenter, prospective trial of non-endoscopic biomarker-driven detection of Barrett’s Esophagus and Esophageal Adenocarcinoma.” The American Journal of Gastroenterology (2024): 10-14309.
2. Greer, Katarina B et al. “Non-endoscopic screening for Barrett’s Esophagus and Esophageal Adenocarcinoma in at risk veterans.” medRxiv (2024): 2024-03
3. Shaheen, N., et al., Use of the EsoGuard® Molecular Biomarker Test in Non-Endoscopic Detection of Barrett's Esophagus among High-Risk Individuals in a Screening Population. medRxiv, 2024: p. 2024.06.24.24309401.
4. American Cancer Society. Cancer Facts & Figures 2025.
5. Hang Thuy-Van Petal. "The Epidemiology of Esophageal Adenocarcinoma in the United States: Presidential Poster Award: 333." American Journal of Gastroenterology 113 (2018): S185-S186
6. National Cancer Institute. Surveillance, Epidemiology, and End Results Program.